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Lupron Side Effects Fibroids
Lupron
Hormones are naturally occurring chemicals released from one part of the body that affect other parts of the body in the exocrine and endocrine gland systems. Only a small amount of hormone is required to affect necessary changes. During the latter half of the last century, man made hormones have been used to alter bodily processes in a variety of ways, particularly with birth control and aiding cancer treatments.
Lupron is a popular man-made hormone used to control the production of testosterone in men and estrogen in women. This particular hormone is known as a gonadotropin-releasing hormone analog (GnRH analog), which down-regulates the gonadotropin secretion as long as the drug is administered. This effect minimizes both the production of testosterone in men and estradiol in women.
Conditions Treated with Lupron
Lupron injection was first approved by the FDA in 1985 for use to help treat advanced prostate cancer. Since that time, it has also been approved to treat the following conditions as well:
- Endometriosis or fibroids
- Precocious (early) puberty in both male and female children
It is important to remember that Lupron only treats the symptoms of cancer; it does not cure cancer.
Contraindications for Lupron Treatment
Lupron should not be prescribed to women who are pregnant or hope to become pregnant. Women who are breast-feeding should also avoid Lupron treatments. Allergies or hypersensitivity to the following similar drugs should preclude its use:
- Leuprolide
- Buserelin
- Goserelin
- Histrelin
- Nafarelin
Dosage adjustments or special tests may be required for people with the following conditions:
- Osteoporosis, personal or family history
- Undergoing steroid treatments
- Epilepsy
- Asthma
- Migraines
- Heart disease
- Kidney disease
- Depression
Side Effects of Lupron
As with all drugs, serious side effects may result in additional personal injury and even death. Physicians need to ensure proper diagnoses and treatment plans to minimize the risks to their patients. Understanding the potential side effects and detecting problems early help minimize medical negligence on their part. Some of the serious side effects of Lupron include:
- Birth defects
- Bone pain
- Swelling and rapid weight gain
- Lightheadedness
- Problems urinating
- Sudden headache
Other complications may occur and should be known or researched by the treating physician.
Lupron Litigation
Hormone therapy is big business for big drug companies. While they claim to create drugs that are safe and effective, many times the drugs do not seem to be safe enough. The manufacturer of Lupron was convicted of price fixing and criminally charged with fraudulent drug pricing and marketing concerning Lupron. A company that paid out $875 million in damages to settle the criminal and civil charges would probably not hesitate to cut corners in developing a safe drug.
Pharmaceutical litigators defend innocent victims of these mega-corporations whose only concern is their profits. Lawsuits and tort law are the only recourse for seeking compensation for damages caused by callous and uncaring big business.
About the Author
If you have been harmed by a defective drug, please visit the website of defective drug attorneys Schlichter, Bogard & Denton today to learn more; clients from all over the United States are welcome.
Lupron Dangers
Hormones are a complex series of chemicals created by the human body that affect all aspects of growth and development. Only tiny bits of hormone are secreted in the endocrine and exocrine systems to affect the desired changes. Disrupting that delicate balance or homeostasis with hormone therapy is a dangerous proposition. Since its inception in 1985, Lupron has been one of the most prominent hormone treatments available. The sheer numbers of people treated almost ensure that many will encounter Lupron dangers.
What is Lupron?
Lupron is a popular man-made gonadotropin-releasing hormone analog (GnRH analog) used primarily to treat advanced prostate cancer. In effect, it down-regulates gondadotropin secretion for as long as the drug is administered. It reduces the amount of testosterone in men and estradiol in women.
Lupron has also been show to reduce the effects of endometriosis or fibroids. It is also used to treat precocious or early childhood puberty. Depending on the specific conditions being treated and the size and gender of the patients, there are several dosages and strengths that may be used. Since hormones travel through out the body and may affect many different systems, potential problems can develop in a number of areas.
Endocrine System Issues
Lupron affects the production of hormones necessary for the body to function properly at the same time that it limits the symptoms of breast and prostate cancers. Areas that are affected by hormone disruptions are:
- Hot flashes
- Gynecomastia
- Breast tenderness
- Reduced testicle size
- Impotence
In rare instances pituitary apoplexy, which is basically a shut down of the pituitary gland, have been reported. The pituitary gland is the primary gland in control of the endocrine gland system. Pituitary infarction or death may occur within the first two weeks of treatment. Signs of pituitary infarction include:
- Sudden headache
- Vomiting
- Visual changes
- Opththalmoplegia
- Altered mental status
Emergency medical treatment is required if these symptoms occur. Needless to say, this is a very serious Lupron danger.
Genitourinary Tract Issues
Numerous genitourinary tract issues have been linked to Lupron treatments, including:
- Vaginal hemorrhaging
- Massive ascities or fluid build up in tissues
- Vaginal dryness
- Frequent urination
- Hematuria
- Reduced penis size
Cardiovascular Side Effects
Some of the cardiovascular changes related to Lupron include:
- ECG changes
- Ischemia
- Peripheral edema
- Hypertension
- Hypotension
Numerous other issues seem to be related to adverse effects of Lupron treatments, but the drug continues to be used to treat a number of medical conditions. The risks of treatment must be weighed against the benefits the drug offers.
About the Author
If you have been harmed by a defective drug, please visit the website of defective drug attorneys Schlichter, Bogard & Denton today to learn more; clients from all over the United States are welcome.
